Pituranthos chloranthus Oil as an Antioxidant-Based Adjuvant Therapy against Cisplatin-Induced Nephrotoxicity
نویسندگان
چکیده
منابع مشابه
Effect of infliximab against cisplatin-induced nephrotoxicity
OBJECTIVES To investigate whether infliximab (Ib), an inhibitor of tumor necrosis factor alpha (TNF-α), prevents cisplatin (Cis)-induced nephrotoxicity. METHODS The study was performed in the Department of Internal Medicine, Recep Tayyip Erdogan University, Rize, Turkey, between November 2012 and May 2013. Thirty male Wistar albino rats were divided into 3 groups, a control group, a Cis group...
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Background: Nephrotoxicity is an inherent of certain anticancer drugs. Aim: This study aimed to assess the protective effect of onion oil and selenium against cisplatin-induced nephrotoxicity in male rats. Results: Cisplatin (5 mg/kg, i.p.) caused significant increases in serum sodium, blood urea nitrogen, serum creatinine, total sodium and potassium excreted in urine, urine volume and lipid pe...
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The importance of Tinospora cordifolia stem extract was investigated for its possible curative effect in male wistar rats against the cisplatin induced nephrotoxicity. Oral administration of plant extract cured the cisplatin induced kidney damage. There was an increase in serum creatinine, blood urea nitrogen and alkaline phosphatase in rats treated with Cisplatin (5mg/kg body weight, i.p). Adm...
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Objective(s) Portulaca oleracea L. is a herbaceous weed from portulacaceae family. It can be found in many parts of the world. Modern pharmacological studies have demonstrated that P. oleracea have antioxidant effects. The protective effect of aqueous and ethanolic extract of P. oleracea against cisplatin-induced renal toxicity was studied in rats. Materials and Methods Single intraperitonea...
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Objective: The clinical use of cisplatin is highly restricted, because of its nephrotoxicity.In this study the protective effect of Nigella sativa (N. sativa) against cisplatin-induced nephrotoxicity was investigated in rats. Materials and Methods: In the current study, the effects of the administration of aqueous-ethanolic extract of N. sativa (100 and 200 mg/kg, BW) and vitamin E (100 mg/kg, ...
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ژورنال
عنوان ژورنال: Journal of Toxicology
سال: 2020
ISSN: 1687-8191,1687-8205
DOI: 10.1155/2020/7054534